I personally enjoyed Lost much more than The X-Files (even though I've only made it to about half-way through Season 6 of the latter). One thing I really like is the interconnection of all the stories in Lost. The X-Files includes an incredibly high number of episodes that are disconnected from the main storyline (as Wikipedia refers to them, "Monster of the Week" episodes). In Lost, though, every episode, and every flashback, is connected (or at least, is supposed to be--some might debate how much that succeeded). I also think Lost is heavier on relationships, maybe because it has many more relationships, due to its vast number of characters. Lost is definitely an amazing show, though!