I think it’s time to remind people that, despite claims to the contrary, the ECFs did not view the Lord’s Supper as a mere memorial remembrance, nor the bread and wine as mere metaphors. All selections are from the excellent Ancient Christian Commentary on Scripture New Testamant v IVa (John 1-10).
Ambrose (fl 374-97):
It has been proven that the sacraments of the church are more ancient; now realize that they are more powerful. In very fact it is a marvelous thing that God rained manna on the ancestors and they were fed by daily nourishment from heaven. Therefore, it is said, “Humankind has eaten the bread of the angels.” And yet all those who ate that bread died in the desert, but this food that you receive, this “living bread, which came down from heaven”, furnishes the substance of eternal life, and whoever eats this bread “will not die forever” for it is the body of Christ. (On the Mysteries 8.47).
Ephrem the Syrian (fl 363-73):
He called the bread his living body and he filled it with himself and with his Spirit. He stretched forth his hand and gave them the bread that his right hand had sanctified: “Take, eat, all of you of this bread that my word has sanctified. Do not regard as bread what I have given you now…eat it, and do not disdain its crumbs. For this bread that I have sanctified is my body. Its least crumb sanctifies thousands of thousands, and it is capable of giving life to all who eat it. Take, eat in faith, doubting not at all that this is my body. And he who eats it in faith eats in it fire and the Spirit. If anyone doubts and eats it, it is plain bread to him. He who believes and eats the bread sanctified in my name, if he is pure, it will keep him pure; if he is a sinner, he will be forgiven. He, however, who despises it or spurns it, he may be sure that he is insulting the Son, who has called the bread his body and truly made it so. Receive of it, eat of it, all of you, and eat in it the Holy Spirit, for it is truly my body, and he who eats it will live forever. This is the heavenly bread that has come down from high onto the earth. This is the bread that the Israelites ate in the wilderness and did not esteem. The manna that they gathered, which came down to them, was a figure of this spiritual bread that you now have received. Take and eat of it, all of you. In this bread you are eating my body. It is the true source of forgiveness.” (Memra for the Fifth Day of Great Week (Holy Thursday), Sermon 4.