Mosquitoes 'resist malaria drugs'

This is terrible news. The artemesinin drugs have only been available to the world for about 15 years, and were rushed into development because all of the older anti-malaria drugs have been largely ineffective.

International scientists say they have found the first evidence of resistance to the world’s most effective drug for treating malaria.

They say the trend in western Cambodia has to be urgently contained because full-blown resistance would be a global health catastrophe.

“Twice in the past, South East Asia has made a gift, unwittingly, of drug resistant parasites to the rest of the world, in particular to Africa,” he said.

“That’s the problem. We’ve had chloroquine and SP resistance, both of which have caused major loss of life in Africa,” in said in reference to earlier generation anti-malarial drugs.

“If the same thing happens again, the spread of a resistant parasite from Asia to Africa, that will have devastating consequences for malaria control,” he said.

news.bbc.co.uk/2/hi/asia-pacific/8073118.stm

A slight correction. It is the Plasmodium parasites that have evolved a resistence to the drugs, not the mosquitos. Mosquitos are only the host for the parasite, not the cause of the actual disease.

Peace

Tim

Yes, you are absolutely correct. It is the Plasmodium species (several protozoa) which cause Malaria, not the mosquito itself. The mosquito is simply the means by which the Malaria-causing protozoan spreads from human to human.

Just to help persons put this into perspective, Malaria currently is the cause of 8% of all deaths in the world.
cdc.gov/malaria/impact/index.htm

If the artemesinin drug resistance spreads, the death toll will rise.

The Bill and Melinda Gates foundation is funding projects to combat the disease… there is HOPE…

Malaria:
This insect-borne disease kills more than 1 million people annually. Promising projects include development of vaccines to prevent malaria and genetic strategies to reduce or incapacitate populations of disease-transmitting insects.
GOAL 2 | CHALLENGE 5
Enhancing the Immunogenicity and Efficacy of Vectored Vaccines
GOAL 2 | CHALLENGE 5
Protective Genetically Attenuated P. Falciparum Sporozoite Vaccine
GOAL 2 | CHALLENGE 5
Improved Vaccine Efficacy via Dendritic Cells and Flavivirus Vectors
GOAL 2 | CHALLENGE 6
Protective Immunity Against Severe Malaria in Young Children
GOAL 2 | CHALLENGE 6
Learning From the Human Genome How Protective Immunity Against Malaria Works
GOAL 3 | CHALLENGE 7
Homing Endonuclease Genes: New Tools for Mosquito Population Engineering and Control
GOAL 3 | CHALLENGE 7
Developing Coupled Transgenic Ribozyme and Insecticide Resistance Approaches to Establishing Dengue Virus Refractoriness in Natural Populations of Aedes aegypti Mosquitoes
GOAL 3 | CHALLENGE 8
Molecular Approaches to Alter Olfactory Driven Behaviors of Insect Disease Vectors
GOAL 3 | CHALLENGE 8
Molecular Design of Selective Anticholinesterases for Mosquito Control
GOAL 3 | CHALLENGE 8
Disruption of Malaria Transmission by Chemical Manipulation of Anopheline Olfactory Responses
GOAL 5 | CHALLENGE 10
Novel Therapeutics that Boost Innate Immunity to Treat Infectious Diseases
GOAL 7 | CHALLENGE 13
Population Health Metrics Research Consortium Project
GOAL 7 | CHALLENGE 14
A Point of Care Diagnostic System for the Developing World
GOAL 7 | CHALLENGE 14
Integrated Rapid Test Platforms Appropriate for the Developing World

grandchallenges.org/Pages/BrowseByDisease.aspx#Malaria

DDT would put an end to it. But it’s not politically correct to employ it.
Make the decision-millions of human lives or maybe the lives of a few birds…Roanoker

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